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Product Name: Uridine
Alias: Uridinato
CAS: 58-96-8
EINECS: 200-407-5
MF: C9H12N2O6
MW: 244.2014
Purity: 99%
MP: 165-170℃
Grade: Pharmaceutical Grade
Appearance: White Crystalline Powder


Uridine is a nutrient that is largely unknown as a dietary supplement and yet, paradoxically, has a well-established place in nutrition. Uridine is a nucleotide base found in high levels in beer which is used for increasing synthesis of cellular membranes and for other neurological properties.

Uridine is a component of RNA that has positive health effects on humans. It can help improve brain function and aid in treating mental disorders, reduce pain, and protect the heart. It appears to have potentially cognitive enhancing properties, and is synergistic with fish oil.

Uridine Benefits

Uridine is shown to lead to a number of beneficial Nootropic effects. Some of these include improving working memory and enhanced fluid intelligence. Supplementation can allow you to write, read, or simply just concentrate on a task at hand with what seems like much less conscious effort. Most of these effects are due to the supplement converting into Choline and then Acetylcholine.

Given the mechanisms of action for Uridine it may not be surprising that many researchers feel it can help to slow down the process of brain aging. As a result, there is even speculation regarding its ability to fight off depression and prevent certain forms of dementia like Alzheimer’s disease. This is likely due to role that Uridine has as a precursor to RNA.

There also many reports of Uridine supplementation leading an increase in mood and overall motivation levels. This can lead to reduced stress, anxiety, and possibly symptoms of obsessive compulsive disorders. There is evidence suggesting that Uridine may be effective in the treatment of depression.

Another interesting effect of this supplement is that it repairs brain membrane fluidity, so scientists think that it might actually improve the health of your brain cells.


Stacking this nootropic with choline sources or omega-3 supplements may enhance and increase cognition to higher levels within the brain. The choline sources commonly used with Uridine are CDP Choline or Alpha GPC. Uridine has been shown to have anti-depressant properties and may increase some level of dopamine within the brain.  Uridine has been often paired or stacked with omega-3 and n-3 fats in order to amplify the anti-depressant and mood enhancement effects.


Supplementation of uridine seems to be in the 500-1,000mg range, with the lone human study using the higher end of this range. It is recommended to take uridine with food out of prudency, but this has not been noted to be an absolute requirement.

Uridine Side Effects

As long as the dosage recommendations are followed, the only side effects that might be present include headaches, fatigue, nervousness, and some gastrointestinal distress. Of course, these are usually very mild and usually the result of taking too large of a dose.

There is also some evidence to suggest that this supplement may lower levels of vitamin B12. The solution to this is to take a B12 and B9 supplement. Other studies have shown that the Omega-3 supplement DHA is synergistic when taken in combination with Uridine.


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