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Magnesium L-Threonate

Product Name: Magnesium L-Threonate
CAS: 778571-57-6
MF: C8H14MgO10
MW: 294.49576
Purity: 95%
Grade: Food Grade
Appearance: White Powder



Magnesium L-Threonate (MgT) is a new form of the basic element magnesium. By increasing overall neural health and function via synaptogenesis, MgT contributed to long term neuro-protective health, staving off common memory loss due to aging. It is derived from L-Threonic acid.

Magnesium L-Threonate might represent a more efficient method for achieving regular magnesium sulfate’s well-known cognitive benefits. It improved short-term memory, long-term memory, and learning ability in test subjects.

While it is not appropriate for people with kidney or heart conditions, it is at least as safe and effective as a standard magnesium sulfate supplement, which is taken widely.

In recent studies done at MIT and Beijing's Tsinghua University, Magnesium L-Threonate was found to dramatically increase the activity and plasticity of synapses. That means these connections between neurons were more inclined to grow and exhibit healthy, efficient communication behaviors.

This was especially true in the hippocampus, home of all memory function in the human brain. Magnesium L-Threonate may achieve this effect partly by increasing cerebrospinal fluid in the brain.


The synaptic activity generated by Magnesium L-Threonate resulted in notable increases in various types of memory in test subjects. Memory recall was increased, especially in older subjects. This indicates that MgT could have a slowing effect upon normal age-related memory decline. As the neural tissues age, they become increasingly inflexible and less inclined to new synaptic growth. This process results in memory loss and the general inability to learn new things and create new neural pathways in the process. Scientists hope that MgT can address this problem.

For those that experience chronic neuropathic pain, this supplement can help relieve one’s discomfort. With that being said, there has been some discussion based on Magnesium L-Threonate vs. Magnesium Sulfate. Both of these compounds tend to improve memory, however, Magnesium L-Threonate tends to be safer.

These benefits are in addition to standard magnesium benefits such as improved bone strength, better nerve function, and general increases in mental and physical energy through glucose production.

When people are deficient in magnesium, they tend to experience an irregular heartbeat. By taking this supplement, this issue can be alleviated. Due to possible deficiencies, magnesium supplements are also used to promote better nerve function. This mineral acts as a natural muscle relaxant, allowing your body and mind to reach a calming state. This has been shown as an effective aid regarding both insomnia and restless leg syndrome.


The standard dose for an adult, is generally between 200-400 mg. On average, males typically take 400 mg daily, while women take around 300 mg. When purchasing commercial Magnesium L-Threonate, you can find doses as large as 2000 mg per one single serving.

However, when taking a dose this size, it's important to note that it will equate to approximately 140 mg of elemental magnesium. While taking magnesium supplements, many users will stack with calcium. Typically, this stack will be 1 part magnesium: 3 parts calcium.

If you're looking to take Magnesium L-Threonate for its cognitive benefits, then it’s recommended that you stack with Oxiracetam. This racetam, inhibits the antagonism of NMDA receptors. Due to these effects, users can experience even greater plasticity in the brain.

Magnesium L-Threonate tends to have better absorption rates, producing more intense cognitive effects. As more research develops, Magnesium L-Threonate could eventually become the most common and most preferred method for consuming magnesium.

Side Effects

If you take too much magnesium, this could lead to potentially serious side-effects. For some users, taking very large doses, can lead to low blood pressure, severe brain fog, and an irregular heartbeat. In extreme, rare cases, overdoses can result in death.

If you have issues with your kidneys, then magnesium supplements should be avoided. This of course also relates to anyone that is taking kidney-related medication. When you add more magnesium to your routine, it can be become overwhelming for your kidneys.


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