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Mequitazine

Chemical Name:Mequitazine
Molecular Formula:C20H22N2S
Formula Weight:322.47
CAS No.:29216-28-2
Apperance: white powder
Purity:99%
Grade:Pharmaceutical Grade
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Description

What is Mequitazine ?


It is of Synthetic origin and belongs to Phenothiazine. It belongs to H1-antagonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Mequitazine is 322.50.Its pKa is 8.66.


Indications

Mequitazine is primarily indicated in conditions like Allergy, Hay fever, Insect bites, Pruritus, Rhinitis, Urticaria, and can also be given in adjunctive therapy as an alternative drug of choice in Conjuctivitis.


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Pharmacokinetics

Oral absorption of Mequitazine is found to be 70% . Volume of distribution is found to be 400 litre and plasma protien binding is 90 %. and metabolism is reported Hepatic. Renal Excretion accounts for 1 % and plasma half life is 40 hr.

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Mequitazine dosage:


Adult Dosage: 5mg/12 hours


Mequitazine Side Effects:


The symptomatic adverse reactions produced by Mequitazine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Depression, dizziness.


Description

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