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Memantine HCl

Product Name: Memantine HCL
Alias: Memantine Hydrochloride
CAS: 41100-52-1
EINECS: 255-219-6
MF: C12H22ClN
MW: 215.7628
Purity: 99%
MP: 292 °C
BP: 239.8°C at 760 mmHg
FP: 92.3°C
Grade: Pharmaceutical Grade
Appearance: White Crystalline


Memantine HCL is an oral medication for the treatment of moderate to severe dementia associated with Alzheimer's. Memantine HCL's effects are independent of acetylcholine and acetylcholinesterase. 

It is believed that too much stimulation of nerve cells by glutamate may be responsible for the degeneration of nerves that occurs in some neurological diseases such as Alzheimer's disease. Glutamate is produced and released by nerve cells in the brain. The released glutamate then travels to nearby nerve cells where it attaches to a receptor on the surface of the cells called the N-methyl-D-aspartate (NMDA) receptor.

Memantine HCL blocks this receptor and thereby decreases the effects of glutamate. It is thought that by blocking the NMDA receptor and the effects of glutamate, memantine may protect nerve cells from excess stimulation by glutamate.


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