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Meclofenoxate HCl

Product Name: Centrophenoxine
Alias: Centrophenoxine HCL,Lucidril,Meclofenoxate HCL
CAS: 3685-84-5
EINECS: 222-975-3
MF: C12H17Cl2NO3
MW: 294.17
Purity: 99%
MP: 133-135°C
BP: 345.9°C at 760 mmHg
FP: 163°C
Grade: Pharmaceutical Grade
Appearance: White Powder



Centrophenoxine, also known as meclofenoxate or Lucidril, is a well-known and respected nootropic that has been proven over five decades of use and rigorous clinical testing. It's a powerful nootropic and memory booster in its own right, and it's also an excellent choline source for use in combination with other nootropics.

Developed in 1959 by scientists at the French National Scientific Research Center, centrophenoxine was created as a treatment for Alzheimer's disease and other forms of cerebral insufficiency and age-related cognitive decline. While it is still prescribed for the treatment of age-related memory loss in Europe, it is available over the counter as a dietary supplement in the US and is most frequently used for its nootropic or cognitive enhancement properties.

Centrophenoxine is classified as a cholinergic, a substance that delivers or enhances the action of choline. It's this cholinergic capability that makes it an efficient and effective nootropic on its own and a powerful potentiator when used in combination with other nootropics, particularly the racetams.

It is effective in reversing some of the signs of aging (particularly waste product buildup in the brain) when taken for an acute period (high doses for a month) and can act as a general neural enhancer and protector when taken continuously at a lower dose.


Better Memory

Centrophenoxine is best known for its considerable abilities as a memory booster. Its primary action is providing additional choline and enabling the production of acetylcholine, the neurotransmitter that is most closely tied to cognitive function in general and memory in particular.

Enhanced Fluid Intelligence

Centrophenoxine can enhance fluid intelligence, or the ability to solve problems without relying on acquired knowledge.

Improved Overall Brain Function

Centrophenoxine is considered a neuro energizer because it stimulates glucose uptake, oxygen consumption, and carbon dioxide production. The additional oxygen and glucose add to its nootropic effects, making learning easier, thought clearer, and all of the brain's functions more efficient.

Increased Energy

Many users find that centrophenoxine has a mild stimulant effect. While it energizes without creating the jittery feelings that amphetamines or other stimulants cause, its energy boost is enough to disrupt regular sleep patterns if taken late in the day.


Research shows that centrophenoxine is an aggressive free radical scavenger and powerful antioxidant that protects the brain from age-related deterioration, flushes out toxins, and repairs damaged cells.

Mood and Motivation

Users report that centrophenoxine has a strong motivating and mood-improving effect, acting as a mild but noticeable anti-depressant.


A typical dose when taking as a nootropic, either on its own or in a stack, is 250 mg. A cumulative daily dosage ranging from 500-1000 mg is considered both safe and effective for most healthy adults interested in centrophenoxine's cognitive and nootropic benefits. Higher doses may be required to maximize its anti-aging effects, but it is advisable to consult a medical professional before exceeding the recommended daily dosage.

As with all supplements, it is best to start with the lowest possible effective dose and build gradually as needed.

Because centrophenoxine is fat-soluble, it is best taken with food. Its mild stimulant effect could potentially interrupt sleep patterns if taken late in the day.

Side Effects

Centrophenoxine is considered to be very safe and high in tolerability. However, possible side effects may include, rarely, insomnia, dizziness, restlessness, muscle tremor, depression, nausea, muscle tension, and headache; these side effects may be due to overdosage and may indicate the need for the dosage to be reduced.


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