Antidepressant

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Escitalopram

Product Name:Escitalopram
CAS NO.:128196-01-0
Molecular Formula:C20H21FN2O
Molecular Weight:324.39
Purity:99%
Appearance:White Powder
Grade:Pharmaceutical Grade
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Description

Escitalopram, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Escitalopram is the (S)-stereoisomer (Left-enantiomer) of the earlier Lundbeck drug citalopram, hence the name escitalopram. Whether escitalopram exhibits superior therapeutic properties to citalopram or merely represents an example of "evergreening" is controversial.


Medical Uses


Escitalopram has FDA approval for the treatment of major depressive disorder in adolescents and adults, and generalized anxiety disorder in adults.In European countries and Australia, it is approved for depression (MDD) and certain anxiety disorders: general anxiety disorder (GAD), social anxiety disorder (SAD), obsessive-compulsive disorder (OCD), and panic disorder with or without agoraphobia.


Depression


Escitalopram was approved by regulatory authorities for the treatment of major depressive disorder on the basis of four placebo controlled, double-blind trials, three of which demonstrated a statistical superiority over placebo.


Anxiety disorder


There may be a significant improvement in GAD symptoms as early as the first week and the majority of patients respond by week eight with a significant improvement in functioning.It also seems effective in the long-term, with relapse on escitalopram (20%) less than placebo (50%).

Escitalopram and citalopram appear equally effective in panic disorder.


Description

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