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Dibucaine Hcl 61-12-1

Dibucaine hydrochloride
CAS:61-12-1
EINECS number:200-498-1
Molecular formula:C20H31Cl2N3O2
Molecular weight:416.385
MP:99-101 º C
Boiling point:544.7 ° C at 760 mmHg
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Description

Dibucaine hydrochloride


CAS:61-12-1

EINECS number:200-498-1

Molecular formula:C20H31Cl2N3O2

Molecular weight:416.385

MP:99-101 º C

Boiling point:544.7 ° C at 760 mmHg

Flash Point:283.2 ° C

Vapor Pressure:3.37E-12mmHg at 25 ° C

MP 99-101 ° C

Use:Anesthetic (local),Pharmaceutical raw materials

Packing:Foil bag or as requirments

 

Pharmacological pharmacokinetics


Although the chemical structure of cinnamic acid hydrochloride amide, but still and local anesthetic local esters, plasma cholinesterase can be hydrolyzed, clinically and can be used to identify the effect of the esterase. Local anesthesia than procaine 22 to 25 times, long duration, but the toxicity of procaine than 15-20 times, once poisoning, rescue takes 4-8 hours to reverse.

In the organization than procaine stable, so the duration of anesthesia for a long time (about three times that of procaine).

 

Indications


For epidural anesthesia and spinal anesthesia. This product is easy through the mucosa, but also for surface anesthesia, but because of its toxicity is too large (about 15 times higher than procaine), less for infiltration anesthesia.

Dosage and Usage

Limited to adult subarachnoid block, generally limited to 10mg, shall not exceed 15-20mg.



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